ABCA4 antibody

$275.00

  • Model: PAab09922
  • 50 Units in Stock
Ask a question


Add to Cart: Min:  0 Units:  0

ABCA4 antibody


Product Name ABCA4 antibody

Catalog No PAab09922

Packing 100ul

Form liquid

Alternative Name ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Immunogen ABCA4

Specificity Human, Mouse, Rat

Tested Application ELISA, WB, IF

Recommended dilution WB: 1:500 - 1:2000; IF: 1:50 - 1:200

IHC use


WB use

BT474 cells were subjected to SDS PAGE followed by western blot with PAab09922 (ABCA4 antibody) at dilution of 1:1000

Protein Information

Gene ID 24

Uniprot ID P78363

Calculated MW 256 kDa

Research Area Neuroscience

No customer comments for the moment.

Add A Comment

Related Products

Cart  

No products

Total $0.00

Prices don't include postage.

Cart