AMOT antibody


  • Model: PAab09852
  • 50 Units in Stock
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AMOT antibody

Product Name AMOT antibody

Catalog No PAab09852

Packing 100ul

Form liquid

Alternative Name AMOT, angiomotin, KIAA1071

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Angiomotin belongs to the motin family of angiostatin binding protein. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Most abundant expression was found in placenta and skeletal muscle. AMOT has two isoforms with MW 130 kDa (p130) and 80 kDa (p80). The p130 isoform can interact with F-actin.This antibody recognizes both p130 and p80.

Immunogen angiomotin

Specificity Human

Tested Application ELISA, WB, IHC, IF, IP

Recommended dilution WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

IHC use Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using PAab09852(AMOT Antibody) at dilution of 1:200

WB use

HEK293 cells were subjected to SDS PAGE followed by western blot with PAab09852(AMOT Antibody) at dilution of 1:1000

Protein Information

Gene ID 154796

Uniprot ID Q4VCS5

Calculated MW 62 kDa

Research Area Cardiovascular, Developmental biology

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