ATP7B antibody
Product Name ATP7B antibody
Catalog No PAab09849
Packing 100ul
Form liquid
Alternative Name PWD, WC1, WD, WND
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).
Immunogen ATP7B
Specificity Human, Mouse
Tested Application ELISA, WB, IF
Recommended dilution WB: 1:500 - 1:2000; IF: 1:50 - 1:200
IHC use
WB use
mouse liver tissue were subjected to SDS PAGE followed by western blot with PAab09849( ATP7B antibody ) at dilution of 1:1000
Protein Information
Gene ID 540
Uniprot ID P35670
Calculated MW 30 kDa
Research Area Signal Transduction, Metabolism