ATP7B antibody

$275.00

  • Model: PAab09904
  • 50 Units in Stock
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ATP7B antibody


Product Name ATP7B antibody

Catalog No PAab09904

Packing 100ul

Form liquid

Alternative Name PWD, WC1, WD, WND

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Immunogen ATP7B

Specificity Human

Tested Application IHC

Recommended dilution IHC: 1:50 - 1:200

IHC use Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab09904( ATP7B antibody) at dilution of 1:100


WB use

Protein Information

Gene ID 540

Uniprot ID P35670

Calculated MW 30 kDa

Research Area Metabolism, Signal Transduction

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