BDNF antibody


  • Model: PAab10014
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BDNF antibody

Product Name BDNF antibody

Catalog No PAab10014

Packing 100ul

Form liquid

Alternative Name BDNF, ANON2, BULN2, brain-derived neurotrophic factor

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation(LTP), long-term depression(LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Immunogen brain-derived neurotrophic factor

Specificity Human, Rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:200-1:2000; IHC: 1:50-1:500

IHC use Immunohistochemistry of paraffin-embedded rat brain tissue slide using PAab10014(BDNF Antibody) at dilution of 1:200

WB use

A549 cells tissue were subjected to SDS PAGE followed by western blot with PAab10014(BDNF Antibody) at dilution of 1:1000

Protein Information

Gene ID 627

Uniprot ID P23560

Calculated MW 28-37 kDa, 14 kDa

Research Area Neuroscience, Signal Transduction, Developmental biology

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