CASP14 antibody

$275.00

  • Model: PAab09900
  • 50 Units in Stock
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CASP14 antibody


Product Name CASP14 antibody

Catalog No PAab09900

Packing 100ul

Form liquid

Alternative Name CASP14, ARCI12, caspase-14

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Immunogen CASP14

Specificity Human, Mouse, Rat

Tested Application ELISA, WB, IF

Recommended dilution WB: 1:500 - 1:2000; IF: 1:50 - 1:200

IHC use


WB use

293T cells were subjected to SDS PAGE followed by western blot with PAab09900( CASP14 antibody) at dilution of 1:1000

Protein Information

Gene ID 23581

Uniprot ID P31944

Calculated MW 30 kDa

Research Area Cell Division and Proliferation

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