CASP7 antibody
Product Name CASP7 antibody
Catalog No PAab10124
Packing 100ul
Form liquid
Alternative Name CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen caspase-7
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IHC, IF
Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
IHC use Immunohistochemistry of paraffin-embedded rat heart using PAab10124(CASP7 antibody) at dilution of 1:100
WB use
293T cells were subjected to SDS PAGE followed by western blot with PAab10124( CASP7 Antibody) at dilution of 1:1000
Protein Information
Gene ID 840
Uniprot ID P55210
Calculated MW 37kDa
Research Area