Caspase 2 antibody


  • Model: PAab098281
  • 50 Units in Stock
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Caspase 2 antibody

Product Name Caspase 2 antibody

Catalog No PAab098281

Packing 100ul

Form liquid

Alternative Name CASP 2, CASP2, Caspase 2, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

Immunogen Caspase 2

Specificity Human

Tested Application ELISA, WB

Recommended dilution WB: 1:1000-1:6000

IHC use

WB use

Jurkat cells were subjected to SDS PAGE followed by western blot with PAab098281 (Caspase 2 antibody) at dilution of 1:3000

Protein Information

Gene ID 835

Uniprot ID P42575

Calculated MW 34 kDa

Research Area Neuroscience, Immunology, Signal Transduction

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