CD14 antibody

$275.00

  • Model: PAab10077
  • 50 Units in Stock
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CD14 antibody


Product Name CD14 antibody

Catalog No PAab10077

Packing 100ul

Form liquid

Alternative Name CD14, CD14 molecule

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211).

Immunogen CD14 molecule

Specificity Human

Tested Application ELISA, IHC

Recommended dilution IHC: 1:20-1:200

IHC use Immunohistochemistry of paraffin-embedded human kidney tissue slide using PAab10077(CD14 Antibody) at dilution of 1:200


WB use

Protein Information

Gene ID 929

Uniprot ID P08571

Calculated MW 50-55 kDa

Research Area Stem Cells, Immunology, Signal Transduction, Cancer

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