CD150 antibody(PE conjugated)

$275.00

  • Model: PAab09790
  • 50 Units in Stock
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CD150 antibody(PE conjugated)


Product Name CD150 antibody(PE conjugated)

Catalog No PAab09790

Packing 100ul

Form liquid

Alternative Name CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906

Purification Protein G purified

Purity 95% as determined by SDS-PAGE

Host Rat

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies.

Immunogen signaling lymphocytic activation molecule family member 1

Specificity Mouse

Tested Application FC

Recommended dilution 1

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