C-FOS antibody


  • Model: PAab09803
  • 50 Units in Stock
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C-FOS antibody

Product Name C-FOS antibody

Catalog No PAab09803

Packing 100ul

Form liquid

Alternative Name AP 1, C FOS, Cellular oncogene fos, c-FOS, FOS, G0S7, Proto oncogene c Fos

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

c-FOS, also named as Proto-oncogene c-Fos and G0/G1 switch regulatory protein 7, is a 380 amino acid protein, which contains 1 bZIP(basic-leucine zipper) domain and belongs to the bZIP family. FOS is expressed at very low levels in quiescent cells. When cells are stimulated to reenter growth, FOS undergo 2 waves of expression, the first one peaks 7.5 minutes following FBS induction. At this stage, the FOS protein is localized endoplasmic reticulum. The second wave of expression occurs at about 20 minutes after induction and peaks at 1 hour. At this stage, the FOS protein becomes nuclear. The calculated molecular weight of FOS is 40 kDa, but Phosphorylated FOS protein is about 60-65 kDa.

Immunogen Proto oncogene c Fos

Specificity Human, Mouse, Rat

Tested Application ELISA, IF, IHC, WB

Recommended dilution WB: 1:500-1:2000; IHC: 1:200-1:800; IF: 1:50-1:500

IHC use Immunohistochemistry of paraffin-embedded mouse brain tissue slide using PAab09803(c-FOS antibody) at dilution of 1:400

WB use

mouse embryo tissue were subjected to SDS PAGE followed by western blot with PAab09803(c-FOS antibody) at dilution of 1:1000

Protein Information

Gene ID 2353

Uniprot ID P01100

Calculated MW

Research Area Signal Transduction, Immunology, Cancer

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