CXCR3 antibody

$275.00

  • Model: PAab09859
  • 50 Units in Stock
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CXCR3 antibody


Product Name CXCR3 antibody

Catalog No PAab09859

Packing 100ul

Form liquid

Alternative Name CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Immunogen CXCR3

Specificity Human, Mouse

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

IHC use Immunohistochemistry of paraffin-embedded mouse heart using PAab09859(CXCR3 antibody) at dilution of 1:100


WB use

K562 cells were subjected to SDS PAGE followed by western blot with PAab09859(CXCR3 antibody) at dilution of 1:1000

Protein Information

Gene ID 2833

Uniprot ID P49682

Calculated MW 23 kDa

Research Area Stem Cells, Immunology, Signal Transduction

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