DDR1 antibody

$275.00

  • Model: PAab10051
  • 50 Units in Stock
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DDR1 antibody


Product Name DDR1 antibody

Catalog No PAab10051

Packing 100ul

Form liquid

Alternative Name CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing(By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.

Immunogen discoidin domain receptor tyrosine kinase 1

Specificity Human

Tested Application ELISA, WB

Recommended dilution WB: 1:500 - 1:2000

IHC use


WB use

U87MG cells were subjected to SDS PAGE followed by western blot with PAab10051(DDR1 antibody) at dilution of 1:1000.

Protein Information

Gene ID 780

Uniprot ID Q08345

Calculated MW 101 kDa

Research Area Immunology, Cardiovascular, Metabolism, Signal Transduction

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