Endoglin/CD105 antibody

$275.00

  • Model: PAab10035
  • 50 Units in Stock
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Endoglin/CD105 antibody


Product Name Endoglin/CD105 antibody

Catalog No PAab10035

Packing 100ul

Form liquid

Alternative Name CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen endoglin

Specificity Human

Tested Application ELISA, WB

Recommended dilution WB: 1:200-1:2000

IHC use


WB use

MCF-7 cells were subjected to SDS PAGE followed by western blot with PAab10035(ENG antibody) at dilution of 1:1000

Protein Information

Gene ID 2022

Uniprot ID P17813

Calculated MW 50 kDa, 67 kDa

Research Area Signal Transduction, Cardiovascular, Immunology, Cancer, Developmental biology, Stem Cells

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