FES antibody


  • Model: PAab10031
  • 50 Units in Stock
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FES antibody

Product Name FES antibody

Catalog No PAab10031

Packing 100ul

Form liquid

Alternative Name FPS, Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, FES, p93c-fes

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.

Immunogen Tyrosine-protein kinase Fes/Fps

Specificity Human, Mouse, Rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:500

IHC use Immunohistochemistry of paraffin-embedded rat liver using PAab10031(FES antibody) at dilution of 1:100

WB use

mouse brain were subjected to SDS PAGE followed by western blot with PAab10031(FES antibody) at dilution of 1:1000

Protein Information

Gene ID 2242

Uniprot ID P07332

Calculated MW 98 kDa

Research Area Signal Transduction, Metabolism, cancer

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