FHIT antibody


  • Model: PAab09817
  • 50 Units in Stock
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FHIT antibody

Product Name FHIT antibody

Catalog No PAab09817

Packing 100ul

Form liquid

Alternative Name AP3Aase, FRA3B

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene, a member of the histidine triad gene family, encodes a diadenosine 5', 5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

Immunogen FHIT

Specificity Human, Mouse, Rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

IHC use Immunohistochemistry of paraffin-embedded mouse heart tissue slide using PAab09817( FHIT antibody) at dilution of 1:200

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09817 at dilution of 1:1000

Protein Information

Gene ID 2272

Uniprot ID P49789

Calculated MW 35 kDa

Research Area Metabolism

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