GOT1 antibody


  • Model: PAab09876
  • 50 Units in Stock
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GOT1 antibody

Product Name GOT1 antibody

Catalog No PAab09876

Packing 100ul

Form liquid

Alternative Name AATC, CAT, GIG18, GOT1, Transaminase A

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase(3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

Immunogen glutamic-oxaloacetic transaminase 1, soluble(aspartate aminotransferase 1)

Specificity Human, Mouse, Rat

Tested Application ELISA, IHC, IF, WB

Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100

IHC use Immunohistochemistry of paraffin-embedded human lung cancer using PAab09876(GOT1 antibody) at dilution of 1:100

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09876(GOT1 antibody) at dilution of 1:1000

Protein Information

Gene ID 2805

Uniprot ID P17174

Calculated MW 43-46 kDa

Research Area Neuroscience, Metabolism

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