HSP90AA1 antibody

$275.00

  • Model: PAab09974
  • 50 Units in Stock
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HSP90AA1 antibody


Product Name HSP90AA1 antibody

Catalog No PAab09974

Packing 100ul

Form liquid

Alternative Name HSP 86, HSP86, Hsp89, HSP89A, HSP90, HSP90A, HSP90AA1, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, LAP2

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.

Immunogen heat shock protein 90kDa alpha(cytosolic), class A member 1

Specificity Human, Mouse, Rat

Tested Application ELISA, IHC, WB

Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:200

IHC use Immunohistochemistry of paraffin-embedded rat testis using PAab09974(HSP90AA1 antibody) at dilution of 1:100


WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09974(HSP90AA1 Antibody) at dilution of 1:1000

Protein Information

Gene ID 3320

Uniprot ID P07900

Calculated MW 100 kDa

Research Area Cancer, Signal Transduction

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