LOXL1 antibody

$275.00

  • Model: PAab09975
  • 50 Units in Stock
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LOXL1 antibody


Product Name LOXL1 antibody

Catalog No PAab09975

Packing 100ul

Form liquid

Alternative Name LOL, LOXL, LOXL1, Lysyl oxidase homolog 1, lysyl oxidase like 1, Lysyl oxidase like protein 1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.

Immunogen lysyl oxidase-like 1

Specificity Human, Mouse, Rat

Tested Application ELISA, WB

Recommended dilution WB: 1:500 - 1:2000

IHC use


WB use

A549 cells were subjected to SDS PAGE followed by western blot with PAab09975(LOXL1 Antibody) at dilution of 1:1000

Protein Information

Gene ID 4016

Uniprot ID Q08397

Calculated MW 70kDa

Research Area Cancer, Metabolism

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