MGMT antibody


  • Model: PAab10100
  • 50 Units in Stock
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MGMT antibody

Product Name MGMT antibody

Catalog No PAab10100

Packing 100ul

Form liquid

Alternative Name MGMT

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

Immunogen O-6-methylguanine-DNA methyltransferase

Specificity Human

Tested Application ELISA, IHC

Recommended dilution IHC: 1:50 - 1:500

IHC use Immunohistochemistry of paraffin-embedded human liver cancer using PAab10100(MGMT antibody) at dilution of 1:200

WB use

Protein Information

Gene ID 4255

Uniprot ID P16455

Calculated MW 22 kDa

Research Area Cancer, Immunology, Metabolism

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