NPPB antibody


  • Model: PAab09840
  • 50 Units in Stock
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NPPB antibody

Product Name NPPB antibody

Catalog No PAab09840

Packing 100ul

Form liquid

Alternative Name BNP, BNP(1 32), Natriuretic peptides B, NPPB

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.

Immunogen natriuretic peptide precursor B

Specificity Human

Tested Application ELISA, IHC

Recommended dilution IHC: 1:20-1:200

IHC use Immunohistochemistry of paraffin-embedded human brain slide using PAab09840( BNP Antibody) at dilution of 1:50

WB use

Protein Information

Gene ID 4879

Uniprot ID P16860

Calculated MW 70 kDa

Research Area Stem Cells, Cardiovascular

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