Phospho- MAPK14(T180/Y182) antibody

$350.00

  • Model: PAab10117
  • 50 Units in Stock
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Phospho- MAPK14(T180/Y182) antibody


Product Name Phospho- MAPK14(T180/Y182) antibody

Catalog No PAab10117

Packing 100ul

Form liquid

Alternative Name CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Immunogen A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK

Specificity Human

Tested Application ELISA, WB

Recommended dilution WB: 1:500-1:2000

IHC use


WB use

Hela cells were subjected to SDS PAGE followed by western blot with PAab10117 at dilution of 1:1000

Protein Information

Gene ID 1432

Uniprot ID Q16539

Calculated MW 41kDa

Research Area Cancer, Immunology, Signal Transduction, epigenetics

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