PIK3R1 antibody

Product Name PIK3R1 antibody

Catalog No PAab09963

Packing 100ul

Form liquid

Alternative Name AGM7, GRB1, IMD36, p85, p85-ALPHA

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Immunogen PIK3R1

Specificity Human, Rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

IHC use Immunohistochemistry of paraffin-embedded rat brain tissue slide using PAab09963(PIK3R1 Antibody) at dilution of 1:100

WB use

THP-1 cells were subjected to SDS PAGE followed by western blot with PAab09963(PIK3R1 antibody) at dilution of 1:1000

Protein Information

Gene ID 5295

Uniprot ID P27986

Calculated MW 95kDa

Research Area Immunology, Metabolism, Cancer, Signal Transduction