PKC gamma antibody


  • Model: PAab10007
  • 50 Units in Stock
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PKC gamma antibody

Product Name PKC gamma antibody

Catalog No PAab10007

Packing 100ul

Form liquid

Alternative Name PKC gamma, PKCC, PKCG, PRKCG, Protein kinase C gamma type, protein kinase C, gamma, SCA14

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.

Immunogen protein kinase C, gamma

Specificity Mouse, Rat

Tested Application ELISA, WB, IHC

Recommended dilution WB: 1:500-1:2000; IHC: 1:100-1:500

IHC use Immunohistochemistry of paraffin-embedded rat brain tissue slide using PAab10007(PRKCG Antibody) at dilution of 1:200

WB use

mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab10007(PRKCG antibody) at dilution of 1:1000

Protein Information

Gene ID

Uniprot ID P63318

Calculated MW 78 kDa

Research Area Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience

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