PRKCQ antibody

$275.00

  • Model: PAab10092
  • 50 Units in Stock
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PRKCQ antibody


Product Name PRKCQ antibody

Catalog No PAab10092

Packing 100ul

Form liquid

Alternative Name PRKCQ, PRKCT, nPKC-theta, protein kinase C theta

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.

Immunogen PRKCQ

Specificity Human

Tested Application ELISA, IHC

Recommended dilution IHC: 1:50 - 1:200

IHC use Immunohistochemistry of paraffin-embedded human colon cancer using PAab10092(PRKCQ antibody) at dilution of 1:50


WB use

Protein Information

Gene ID 5588

Uniprot ID Q04759

Calculated MW 85 kDa

Research Area Cell Division and Proliferation, Signal Transduction, Metabolism, cancer, Immunology

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