SOCS1 antibody

$275.00

  • Model: PAab09926
  • 50 Units in Stock
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SOCS1 antibody


Product Name SOCS1 antibody

Catalog No PAab09926

Packing 100ul

Form liquid

Alternative Name CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Immunogen Suppressor of cytokine signaling 1

Specificity Human, Mouse, Rat

Tested Application ELISA, WB

Recommended dilution WB: 1:500 - 1:2000

IHC use


WB use

mouse lung were subjected to SDS PAGE followed by western blot with PAab09926 (SOCS1 antibody) at dilution of 1:1000

Protein Information

Gene ID 8651

Uniprot ID O15524

Calculated MW 24 kDa

Research Area Metabolism, Signal Transduction

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