SRC antibody

Product Name SRC antibody

Catalog No PAab10062

Packing 100ul

Form liquid

Alternative Name ASV, c SRC, p60 Src, pp60c src, Proto oncogene c Src, SRC, SRC1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

SRC, also named as SRC1 and p60-Src, belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. It is a non-receptor protein tyrosine kinase that plays pivotal roles in numerous cellular processes such as proliferation, migration, and transformation. In concert with PTK2B, SRC plays an important role in osteoclastic bone resorption. It promotes energy production in osteoclasts by activating mitochondrial cytochrome C oxidase.

Immunogen v-src sarcoma(Schmidt-Ruppin A-2) viral oncogene homolog

Specificity Human

Tested Application ELISA, IHC

Recommended dilution IHC: 1:20-1:200

IHC use Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using PAab10062(SRC Antibody) at dilution of 1:200

WB use

Protein Information

Gene ID 6714

Uniprot ID P12931

Calculated MW 55kd,60kd

Research Area Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology