TSH Beta antibody

Product Name TSH Beta antibody

Catalog No PAab09807

Packing 100ul

Form liquid

Alternative Name CHNG4, Thyrotropin alfa, Thyrotropin beta chain, Thyrotropin subunit beta, TSH B, TSH BETA, TSHB

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

Immunogen TSHB

Specificity Human, Mouse

Tested Application ELISA, WB, IHC, IF

Recommended dilution WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100

IHC use Immunohistochemistry of paraffin-embedded mouse lung tissue slide using PAab09807( TSH beta antibody) at dilution of 1:100

WB use

Protein Information

Gene ID 7252

Uniprot ID P01222

Calculated MW 16 kDa

Research Area Cancer, Immunology, Signal Transduction