Vinculin antibody

$275.00

  • Model: PAab09799
  • 50 Units in Stock
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Vinculin antibody


Product Name Vinculin antibody

Catalog No PAab09799

Packing 100ul

Form liquid

Alternative Name CMD1W, Metavinculin, MVCL, VCL, Vinculin

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Immunogen vinculin

Specificity Human, Mouse, Rat

Tested Application ELISA, IHC, WB

Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:200

IHC use Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using PAab09799( Vinculin Antibody) at dilution of 1:100


WB use

HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09799(Vinculin Antibody) at dilution of 1:1000

Protein Information

Gene ID 7414

Uniprot ID P18206

Calculated MW 124 kDa

Research Area Immunology, Cardiovascular

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