Vinculin antibody


  • Model: PAab09800
  • 50 Units in Stock
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Vinculin antibody

Product Name Vinculin antibody

Catalog No PAab09800

Packing 100ul

Form liquid

Alternative Name CMD1W, Metavinculin, MVCL, VCL, Vinculin

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament(F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin(124 kDa), is muscle-specific.

Immunogen vinculin

Specificity Human, Rat, Mouse

Tested Application ELISA, FC, IF, IHC, WB

Recommended dilution WB: 1:2000-1:20000; IHC: 1:50-1:500; IF: 1:50-1:500

IHC use Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using PAab09800(Vinculin Antibody) at dilution of 1:200

WB use

hela lysates were subjected to SDS PAGE followed by western blot with PAab09800(Vinculin Antibody) at dilution of 1:5000

Protein Information

Gene ID

Uniprot ID P18206

Calculated MW 124 kDa

Research Area Immunology, Cardiovascular

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