Anti-beta-Catenin antibody
Product Information
Product Name: Anti-beta-Catenin antibody
Catalog No.: LSMab09871
Packing: 100ug
Form: liquid
Purity:more than 95% as determined by SDS-PAGE
Purification: protein A+G purified
Host: Mouse
Isotype: IgG1
Storage Condition: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20degrees for 24 months(Avoid repeated freeze / thaw cycles.)
Immunogen Information
Immunogen Name:catenin(cadherin-associated protein), beta 1, 88kDa
Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
Synonyms: b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286,