Anti-CD150 antibody(PE conjugated)
Product Information
Product Name: Anti-CD150 antibody(PE conjugated)
Catalog No.: LSMab09790
Packing: 100ug
Form: liquid
Purity:more than 95% as determined by SDS-PAGE
Purification: Protein G purified
Host: Rat
Isotype: IgG1
Storage Condition: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20degrees for 24 months(Avoid repeated freeze / thaw cycles.)
Immunogen Information
Immunogen Name:signaling lymphocytic activation molecule family member 1
Background: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies.
Synonyms: CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906
Calculated MW: 11kd
Uniprot ID: Q9QUM4
Gene ID:
Validation
Specificity: Mouse
Tested Application: FC
Recommended dilution: 1