Anti-Cytochrome c antibody

Product Information

Product Name: Anti-Cytochrome c antibody

Catalog No.: LSMab098271

Packing: 100ug

Form: liquid

Purity:more than 95% as determined by SDS-PAGE

Purification: Protein A+G purification

Host: Mouse

Isotype: IgG2a

Storage Condition: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20degrees for 24 months(Avoid repeated freeze / thaw cycles.)

Immunogen Information

Immunogen Name:Cytochrome c

Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

Synonyms: CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4

Calculated MW: 150 kDa

Uniprot ID: P99999

Gene ID: 54205

Validation

Specificity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:5000-1:50000; IHC: 1:20-1:800

IHC use: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using LSMab098271( Cytochrome c Antibody) at dilution of 1:600

WB use: Hela cells were subjected to SDS PAGE followed by western blot with LSMab098271(Cytochrome c antibody) at dilution of 1:20000

Caution:

1. Product is used for research only!