anti- HIF1a antibody

$325.00

  • Model: LSMab09940
  • 100 Units in Stock
Ask a question


Add to Cart:

Anti-HIF1a antibody


Product Information

Product Name: Anti-HIF1a antibody

Catalog No.: LSMab09940

Packing: 100ug

Form: liquid

Purity:more than 95% as determined by SDS-PAGE

Purification: protein A+G purified

Host: Mouse

Isotype: IgG1

Storage Condition:


Immunogen Information

Immunogen Name:hypoxia inducible factor 1, alpha subunit(basic helix-loop-helix transcription factor)

Background: Under normal oxygen conditions, HIF1a is continuously produced and destroyed, in a process involving hydroxylation, interaction with von Hippel-Lindau (VHL) protein, polyubiquitylation and subsequent proteasomal degradation. Under hypoxic conditions, hydroxylation is impaired and HIF1a is stabilized. HIF1a localizes in cytoplasm in normoxia, but it can translocate into nuclear in response to hypoxia. The calculated molecular weight of HIF1a is 93 kDa, but the modified protein HIF1a is about 110-120kDa (PMID: 11698256, .PMID: 7539918).

Synonyms: BHLHE78, MOP1, PASD8

Calculated MW: 120 kDa

Uniprot ID: Q16665

Gene ID: 3091


Validation

Specificity: Human

Tested Application: ELISA, IF, WB

Recommended dilution: WB: 1:1000-1:10000; IF: 1:50-1:200

IHC use:

WB use: Cobalt Chloride treated HeLa cells were subjected to SDS PAGE followed by western blot with LSMab09940(HIF1a Antibody) at dilution of 1:5000


Caution:

1. Product is used for research only!

No customer comments for the moment.

Add A Comment

Related Products

Cart  

No products

Total $0.00

Prices don't include postage.

Cart