anti- PARP1 antibody

$325.00

  • Model: LSMab09939
  • 100 Units in Stock
Ask a question


Add to Cart:

Anti-PARP1 antibody


Product Information

Product Name: Anti-PARP1 antibody

Catalog No.: LSMab09939

Packing: 100ug

Form: liquid

Purity:more than 95% as determined by SDS-PAGE

Purification: protein A+G purified

Host: Mouse

Isotype: IgG1

Storage Condition: 0.01MPBS pH 7.4,-20degrees for 24 months(Avoid repeated freeze / thaw cycles.)


Immunogen Information

Immunogen Name:poly (ADP-ribose) polymerase 1

Background: PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.

Synonyms: ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL

Calculated MW: 115 kDa, 89 kDa

Uniprot ID: P09874

Gene ID: 142


Validation

Specificity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500

IHC use: Immunohistochemistry of paraffin-embedded human breast cancer using LSMab09939(PARP1 antibody) at dilution of 1:600

WB use: HeLa cells were subjected to SDS PAGE followed by western blot with LSMab09939(PARP1 Antibody) at dilution of 1:20000


Caution:

1. Product is used for research only!

No customer comments for the moment.

Add A Comment

Related Products

Cart  

No products

Total $0.00

Prices don't include postage.

Cart