Anti-AMOT antibody
Product Name Anti-AMOT antibody
Catalog No PAab00368
Packing 100ug
Form liquid
Alternative Name AMOT antibody, angiomotin antibody, KIAA1071
Purification Protein A+G purification
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG2b
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
Immunogen angiomotin
Specificity Human
Tested Application ELISA,WB,IHC
Recommended dilution WB :1:1000-1:10000;IHC:1:20-1:200
IHC use
Immunohistochemistry of paraffin-embedded human placenta usingAMOT antibody at dilution of 1:100
WB use
GC-7901 cells were subjected to SDS PAGE followed by western blot with PAab00368( AMOT Antibody) at dilution of 1:2000
Protein Information
Gene ID154796
Uniprot ID Q4VCS5
Calculated MW 118kDa
location