Anti-IL1R2 antibody
Product Name Anti-IL1R2 antibody
Catalog No PAab04243
Packing 100ug
Form liquid
Alternative Name IL1RB
Purification Protein A+G purification
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG1
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Immunogen interleukin 1 receptor, type II
Specificity Human,Mouse
Tested Application ELISA,WB,IF
Recommended dilution
IHC use
WB use
Protein Information
Gene ID7850
Uniprot ID P27930
Calculated MW
location