Anti-IL23A antibody

$300.00

  • Model: PAab04256
  • 50 Units in Stock
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Anti-IL23A antibody

Product Name Anti-IL23A antibody

Catalog No PAab04256

Packing 100ug

Form liquid

Alternative Name SGRF

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Immunogen interleukin 23, alpha subunit p19

Specificity Human

Tested Application ELISA,WB,IHC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human pancreas tissue slide using IL23A Antibody at dilution of 1:50

WB use

Untransfeted HEK293 cells (left) and IL23A transfected HEK293 cells (right) were subjected to SDS-PAGE followed by western blot with PAab04256(IL23A monoclonal Antibody) at dilution of 1:1000

Protein Information

Gene ID51561

Uniprot ID Q9NPF7

Calculated MW

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