Anti-ITM2C antibody


  • Model: PAab04419
  • 50 Units in Stock
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Anti-ITM2C antibody

Product Name Anti-ITM2C antibody

Catalog No PAab04419

Packing 100ug

Form liquid

Alternative Name BRI3

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C- terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).

Immunogen integral membrane protein 2C

Specificity Human

Tested Application ELISA,WB,IF

Recommended dilution

IHC use

WB use

Protein Information

Gene ID81618

Uniprot ID Q9NQX7

Calculated MW


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