Anti-KRAS antibody
Product Name Anti-KRAS antibody
Catalog No PAab04642
Packing 100ug
Form liquid
Alternative Name KRAS2 antibody, RASK2
Purification Protein A+G purification
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG2a
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).
Immunogen v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Specificity Human
Tested Application ELISA,WB,IHC,FC
Recommended dilution
IHC use
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using KRAS Antibody at dilution of 1:650 heat mediated antigen retrieved with Tris-EDTA bufferpH9).
WB use
Neuro-2a cells were subjected to SDS PAGE followed by western blot with PAab04642( KRAS Antibody) at dilution of 1:10000
Protein Information
Gene ID3845
Uniprot ID P01116
Calculated MW
location