Anti-KRAS antibody

Product Name Anti-KRAS antibody

Catalog No PAab04642

Packing 100ug

Form liquid

Alternative Name KRAS2 antibody, RASK2

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306).

Immunogen v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Specificity Human

Tested Application ELISA,WB,IHC,FC

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using KRAS Antibody at dilution of 1:650 heat mediated antigen retrieved with Tris-EDTA bufferpH9).

WB use

Neuro-2a cells were subjected to SDS PAGE followed by western blot with PAab04642( KRAS Antibody) at dilution of 1:10000

Protein Information

Gene ID3845

Uniprot ID P01116

Calculated MW

location