Anti-LONP1 antibody


  • Model: PAab04821
  • 50 Units in Stock
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Anti-LONP1 antibody

Product Name Anti-LONP1 antibody

Catalog No PAab04821

Packing 100ug

Form liquid

Alternative Name PRSS15

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single- stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site- specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Immunogen lon peptidase 1, mitochondrial

Specificity Human, Mouse ,Rat

Tested Application ELISA,WB,IHC,IF

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using LONP1 Antibody at dilution of 1:800 heat mediated antigen retrieved with Tris-EDTA bufferpH9).

WB use

Jurkat cells were subjected to SDS PAGE followed by western blot with PAab04821( LONP1 Antibody) at dilution of 1:5000

Protein Information

Gene ID9361

Uniprot ID P36776

Calculated MW


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