Anti-MCRS1 antibody

Product Name Anti-MCRS1 antibody

Catalog No PAab05067

Packing 100ug

Form liquid

Alternative Name INO80Q antibody, MSP58

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602).

Immunogen microspherule protein 1

Specificity Human,Mouse

Tested Application ELISA,WB

Recommended dilution

IHC use

WB use

Protein Information

Gene ID10445

Uniprot ID Q96EZ8

Calculated MW

location