Anti-MME,CD10 antibody


  • Model: PAab05232
  • 50 Units in Stock
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Anti-MME,CD10 antibody

Product Name Anti-MME,CD10 antibody

Catalog No PAab05232

Packing 100ug

Form liquid

Alternative Name Atriopeptidase antibody, CALLA antibody, CD10 antibody, DKFZp686O16152 antibody, Enkephalinase antibody, EPN antibody, membrane metallo endopeptidase antibody, MME antibody, NEP antibody, Neprilysin antibody, Neutral endopeptidase antibody, Neutral endopeptidase 24.11

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).This antibody is specific to MME.

Immunogen membrane metallo-endopeptidase

Specificity Human,Pig

Tested Application ELISA,IHC,WB

Recommended dilution WB:1:500-1:5000;IHC:1:20-1:200

IHC use

Immunohistochemistry of paraffin-embedded human renal cell carcinoma usingMME,CD10 antibody at dilution of 1:100

WB use

pig kidney tissue were subjected to SDS PAGE followed by western blot with PAab05232( MME,CD10 Antibody) at dilution of 1:1000

Protein Information

Gene ID4311

Uniprot ID P08473

Calculated MW 86kDa,observed 100kDa


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