Anti-NENF antibody

$275.00

  • Model: PAab05661
  • 50 Units in Stock
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Anti-NENF antibody

Product Name Anti-NENF antibody

Catalog No PAab05661

Packing 100ug

Form liquid

Alternative Name CIR2 antibody, SPUF

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG2a

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190).

Immunogen neuron derived neurotrophic factor

Specificity Human, Mouse

Tested Application ELISA,IHC,WB

Recommended dilution

IHC use

Immunohistochemistry of paraffin-embedded human cerebellum usingNENF antibody at dilution of 1:50

WB use

human brain tissue were subjected to SDS PAGE followed by western blot with PAab05661(NENF antibody) at dilution of 1:1000

Protein Information

Gene ID29937

Uniprot ID Q9UMX5

Calculated MW

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