Anti-RACGAP1 antibody

$300.00

  • Model: PAab07071
  • 50 Units in Stock
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Anti-RACGAP1 antibody

Product Name Anti-RACGAP1 antibody

Catalog No PAab07071

Packing 100ug

Form liquid

Alternative Name KIAA1478 antibody, MGCRACGAP

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Immunogen Rac GTPase activating protein 1

Specificity Human

Tested Application ELISA,WB,IF

Recommended dilution

IHC use

WB use

Protein Information

Gene ID29127

Uniprot ID Q9H0H5

Calculated MW

location

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