Anti-U2AF35 antibody

Product Name Anti-U2AF35 antibody

Catalog No PAab09138

Packing 100ug

Form liquid

Alternative Name DKFZp313J1712 antibody, FP793 antibody, RN antibody, RNU2AF1 antibody, U2AF1 antibody, U2AF35 antibody, U2AFBP

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

U2 auxiliary factor (U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2 (RNU2) small nuclear RNA auxiliary factor 1 (U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.

Immunogen U2 small nuclear RNA auxiliary factor 1

Specificity Human

Tested Application ELISA,WB,IHC,IP

Recommended dilution WB : 1:500-1:5000;IHC:1:20-1:200;IP:1:200-1:2000

IHC use

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using U2AF35 Antibody at dilution of 1:50

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab09138( U2AF35 Antibody) at dilution of 1:1000

Protein Information

Gene ID7307

Uniprot ID Q01081

Calculated MW 28kDa,0beserved 40kDa

location