Anti-Villin antibody

Product Name Anti-Villin antibody

Catalog No PAab09407

Packing 100ug

Form liquid

Alternative Name VIL antibody, VIL1 antibody, Villin antibody, villin 1

Purification Protein A+G purification

Purity 95% as determined by SDS-PAGE

Host Mouse

Isotype IgG1

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

Villin 1 (VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.

Immunogen villin 1

Specificity Human, Mouse

Tested Application ELISA,WB,IHC,IF,IP

Recommended dilution WB :1:500-1:5000;IHC:1:50-1:2000;IF:1:10-1:100;IP:1:500-1:5000

IHC use

Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using VIL1 Antibody at dilution of 1:50?

WB use

human kidney tissue were subjected to SDS PAGE followed by western blot with PAab09407(VIL1 antibody) at dilution of 1:1000

Protein Information

Gene ID7429

Uniprot ID P09327

Calculated MW 93kDa

location