SOX2 antibody

$325.00

  • Model: PAab10148
  • 100 Units in Stock
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SOX2 antibody

 

Product Information

Catalog No.:                        PAab10148

Size:                                       100μg

Form:                                     liquid

Purification:                        protein A+G purified

Purity:                                   ≥95% as determined by SDS-PAGE

Host:                                      Mouse

Clonality:                             monoclonal

Clone ID:                              1B5

IsoType:                                IgG1

Storage:                                PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20 for 24 months (Avoid repeated freeze / thaw cycles.)

Background

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).

 

Immunogen information

Immunogen:                       SRY(sex determining region Y)-box 2

Synonyms:                           ANOP3, MCOPS3, SOX2, Transcription factor SOX 2

Observed MW:                   34kd

Uniprot ID :                          P48431

 

Application

Reactivity:                           Human, Mouse; other species are not tested. Please decide the specificity by homology

Tested Application:          ELISA, WB, IHC

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:200

Validation:

 

SOX Antibody

 

 

 

Immunohistochemistry of paraffin-embedded mouse brain tissue using SOX2 Antibody at dilution of 1:100

SOX2-Antibody

 

 

MCF-7 cells were subjected to SDS PAGE followed by western blot with SOX2 antibody at dilution of 1:1000

 

 

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