Anti- IRGM antibody

$325.00

  • Model: PAab10968
  • 50 Units in Stock
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Anti-IRGM antibody

 

Product Name Anti-IRGM antibody

Catalog No PAab10968

Packing 100ug

Form liquid

Alternative Name   IFI1;IRGM1;LRG-47;LRG47

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

IRGM encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specificity Human

Tested Application  Human,Mouse,Rat

Recommended dilution   WB 1:500 - 1:1000 IHC 1:20 - 1:50

HC use

Immunohistochemical analysis of formalin-fixed and paraffin-embedded human brain at 5 ug/mL using IRGM antibody

WB use

Western blot analysis of extracts of various cell lines, using anti-IRGM antibodyat 1:1000 dilution.

 

Protein Information

Uniprot ID  A1A4Y4

Calculated MW  32kDa

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