Anti-ACC1 antibody

Product Name Anti-ACC1 antibody

Catalog No PAab00077

Packing 100ug

Form liquid

Alternative Name ACACA Synonyms ACAC antibody, ACACA antibody, ACC antibody, ACC1 antibody, ACCA antibody, Acetyl CoA carboxylase 1

Purification Immunogen affinity purified

Purity 95% as determined by SDS-PAGE

Host Rabbit

Isotype IgG

Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)

Background/ FUNCTION

ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.

Immunogen acetyl-Coenzyme A carboxylase alpha

Specificity Human,Mouse ,Rat

Tested Application ELISA,WB,IHC,IP,IF

Recommended dilution WB :1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200;IP:1:200-1:2000

IHC use

Immunohistochemistry of paraffin-embedded human skeletal muscle usingACACA antibody at dilution of 1:50

WB use

HeLa cells were subjected to SDS PAGE followed by western blot with PAab00077(ACACA antibody) at dilution of 1:500

Protein Information

Gene ID31

Uniprot ID Q13085

Calculated MW 270kDa

location